冯伟伟-环境健康与生态安全研究院

2015年6月博士毕业于江苏大学，获2015年江苏大学优秀博士学位论文。同年入职江苏大学，兼任江苏省诱变剂学会青委会委员。已承担国家自然科学基金青年项目、中国博士后基金和环境化学与生态毒理学国家重点实验室开放基金等7项，在Environmental Pollution、Journal of Environmental Management、Archives of Toxicology、Food and Chemical Toxicology、Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology和Toxicology等国际权威期刊上发表SCI论文80余篇，其中第一作者和第一通讯作者SCI论文23篇，授权发明专利2项。

承担课题：

[1] 邻苯二甲酸单（2-乙基己基）酯暴露对发育期斑马鱼的神经发育毒性及分子机制研究，持久性有毒污染物环境与健康危害湖北省重点实验室开放基金，2022年12月~2024年12月，在研，主持人。

[2] 四溴双酚A及其典型衍生物对水生生物的生态环境风险，江苏省石油化工安全与环保工程研究中心开放基金，2022年6月~2023年6月，在研，主持人。

[3] DEHP对发育期2型糖尿病小鼠学习记忆功能的影响、毒性易感性及机制研究，环境化学与生态毒理学国家重点实验室开放基金（KF2018-02)，2019年~2020年，已结题，主持人。

[4] 邻苯二甲酸二(2-乙基己基)酯暴露对发育期2型糖尿病小鼠内分泌与代谢系统毒性易感性特征及其机制，国家自然科学基金（81602889），2017年~2019年，已结题，主持人。

[5] DEHP对幼龄小鼠内分泌与代谢系统毒性易感的影响机制，中国博士后基金（2017M611741），2017年~2019年，已结题，主持人。

[6] DEHP对幼龄小鼠内分泌与代谢系统毒性易感性及其影响机制，江苏省博士后基金（1701108B），2017年~2019年，已结题，主持人。

[7] 一种新型铬(Ⅲ)配合物的降血糖作用机制研究，江苏大学高级人才启动基金（15JDG146)，2015年~2018年，在研，已结题。

主要发表论文及专利：

科研论文

[1] Feng Weiwei, Xu Tong, Zuo Jiali, Luo Mengna, Mao Guanghua, Chen Yao, Ding Yangyang, Okeke Emmanuel Sunday, Wu Xiangyang *, Yang Liuqing*. The potential mechanisms of TBBPA bis(2-hydroxyethyl) ether induced developmental neurotoxicity in juvenile zebrafish (Danio rerio). Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 2023,265:109530. (SCI, 一区，IF=4.52，Top期刊).

[2] Okeke Emmanuel Sunday, Okoye Charles Obinwanne, Ezeorba Timothy Prince Chidike, Mao Guanghua, Chen Yao, Xu Hai, Song Chang, Feng Weiwei*, Wu Xiangyang*. Emerging bio-dispersant and bioremediation technologies as environmentally friendly management responses toward marine oil spill: A comprehensive review. Journal of Environmental Management. 2022,322:116123. (SCI, 一区，IF=8.91，Top期刊).

[3] Okeke, E.S., Ezeorba, T.P.C., Mao, G. H., Chen, Y., Feng, W.W.*, Wu, X. Y.*, Nano-enabled agrochemicals/materials: Potential human health impact, risk assessment, management strategies and future prospects. Environmental Pollution. 2022.295:118722. (SCI, IF = 9.988, Top期刊).

[4] Okeke Emmanuel Sunday, Ezeorba Timothy Prince Chidike, Okoye Charles Obinwanne, Chen Yao, Mao Guanghua, Feng Weiwei*, Wu Xiangyang*. Environmental and health impact of unrecovered API from pharmaceutical manufacturing wastes: A review of contemporary treatment, recycling and management strategies. Sustainable Chemistry and Pharmacy. 2022.30:100865. (SCI, IF = 5.464).

[5] Okeke Emmanuel Sunday, Ezeorba Timothy Prince Chidike, Okoye Charles Obinwanne, Chen Yao, Mao Guanghua, Feng Weiwei*, Wu Xiangyang*. Analytical detection methods for azo dyes: A focus on comparative limitations and prospects of bio-sensing and electrochemical. Journal of Food Composition and Analysis. 2022.114:104778. (SCI, IF = 4.52).

[6] Okeke Emmanuel Sunday, Ezeorba Timothy Prince Chidike, Chen Yao, Mao Guanghua, Feng Weiwei*, Wu Xiangyang*. Ecotoxicological and health implications of microplastic ‑ associated biofilms: a recent review and prospect for turning the hazards into benefits. Environmental Science and Pollution Research. 2022, 29:70611-70634. (SCI, IF = 5.190).

[7] Ding Yangyang, Xu Tong, Mao Guanghua, Chen Yao, Qiu Xuchun, Yang Liuqing, Zhao Ting, Xu Xiaoxiao, Feng Weiwei*, Wu Xiangyang*. Di-(2-ethylhexyl) phthalate-induced hepatotoxicity exacerbated type 2 diabetes mellitus (T2DM) in female pubertal T2DM mice. Food and Chemical Toxicology. 2021, 149:112003. (SCI, 一区，IF=5.572，Top期刊).

[8] Xu, Tong, Fei, Fan, Ding, Yangyang, Liu, Yongchao, Mao, Guanghua, Yang, Liuqing, Zhao, Ting, Liao, Taotao, Feng, Weiwei*, Wu, Xiangyang*.Study on the comprehensive utilization of solid residues of Flammulina velutipes and vinegar and their application as feed in Eisenia fetida earthworm culture. Environmental Science and Pollution Research. 2021, 28: 49153-49165. (SCI, IF = 5.190).

[9] Feng Weiwei, Liu Yongchao, Ding Yangyang, Mao Guanghua, Zhao Ting, Chen Kun, Qiu Xuchun, Xu Tong, Zhao Xiaofeng, Wu Xiangyang*, Yang Liuqing*. Typical neurobehavioral methods and transcriptome analysis reveal the neurotoxicity and mechanisms of di(2-ethylhexyl) phthalate on pubertal Male ICR mice with type 2 diabetes mellitus. Archives of Toxicology. 2020, 94:1279–1302. (SCI, 一区，IF=5.728，Top期刊).

[10] Feng Weiwei, Wu Xueshan, Mao Guanghua, Zhao Ting, Wang Wei, Chen Yao, Zhang Min, Yang Liuqing *, Wu Xiangyang *. Neurological effects of sub-chronic exposure to dioctyl phthalate (DOP), lead and arsenic, individual and mixtures, in immature mice，Environmental science and pollution research. 2020, 27:9247-9260. (SCI, IF=5.19)

[11] Zhang Weijie, Chen Hui, Ding Yangyang, Xiang Qingfang, Zhao Jie, Feng Weiwei*, Yang Liuqing*. Effect of chromium citrate on the mechanism of glucose transport and insulin resistance in Buffalo rat liver cells. Indian Journal of Pharmacology. 2020, 52(1): 31-38. (SCI, IF=0.902)

[12] Ding Yangyang, Gao Kun, Liu Yongchao, Mao Guanghua, Chen Kun, Qiu Xuchun, Zhao Ting, Yang Liuqing, Feng Weiwei*, Wu Xiangyang*. Transcriptome analysis revealed the mechanism of the metabolic toxicity and susceptibility of di-(2-ethylhexyl)phthalate on adolescent male ICR mice with type 2 diabetes mellitus. Archives of Toxicology. 2019, 93:3183-3206. (SCI, 一区，IF=5.728，Top期刊)

[13] Ding Yangyang, Liu Yongchao, Fei Fan, Yang Liuqing, Mao Guanghua, Zhao Ting, Zhang Zhehan, Yan Mengjiao, Feng Weiwei*, Wu Xiangyang*. Study on the metabolism toxicity, susceptibility and mechanism of di-(2-ethylhexyl) phthalate on rat liver BRL cells with insulin resistance in vitro. Toxicology. 2019, 422:102-120. (SCI, IF=3.265)

[14] Feng Weiwei, Liu Yongchao, Chen Yao, Ding Yangyang, Yan Mengjiao, Feng Yun, Zhao Ting, Mao Guanghua, Yang Liuqing*, Wu Xiangyang*. Improvement high-glucose and insulin resistance mechanism of chromium malate in 3T3-L1 adipocytes based on glucose uptake and insulin sensitivity signaling pathways. RSC Advances. 2019, 9: 114-127. (SCI，IF=3.049)

[15] Feng Weiwei, Li Qian, Wang Wei, Chen Yao, Zhang Weijie, Zhao Ting, Mao Guanghua, Wu Xiangyang, Yang Liuqing *. Influence of chronic toxicity，lipid metabolism, learning and memory ability and related enzyme in sprague-dawley rats by long-term chromium malate supplementation. Biological Trace Element Research. 2019. 187: 243-257. (SCI, IF=2.431)

[16] Feng Weiwei, Ding Yangyang, Zhang Weijie, Chen Yao, Li Qian, Wang Wei, Chen Hui, Feng Yun, Zhao Ting, Mao Guanghua, Yang Liuqing*, Wu Xiangyang*. Chromium malate alleviates high-glucose and insulin resistant in L6 skeletal muscle cells by regulating glucose uptake and insulin sensitivity signaling pathways. BioMetals. 2018. 31: 891-908. (SCI, IF=2.478)

[17] Feng Weiwei, Li Qian, Wang Wei, Zhao Ting, Feng Yun, Li Fang, Mao Guanghua, Chen Yao, Ding Yangyang, Yang Liuqing*, Wu Xiangyang. Pharmacokinetics and bioavailability of chromium malate and its influence on trace metals absorption after oral or intravenous administration. Indian Journal of Pharmacology. 2018, 50:75-83.(SCI, IF=0.902)

[18] Feng Weiwei, Zhao Ting, Mao Guanghua, Wang Wei, Feng Yun, Li Fang, Zheng Daheng, Wu Huiyu, Jin Dun, Yang Liuqing*, Wu Xiangyang*. Type 2 diabetic rats on diet supplemented with chromium malate show improved glycometabolism, glycometabolism-related enzyme levels and lipid metabolism. Plos One. 2015. 10(5). (SCI, IF=3.534)

[19] Feng Weiwei, Mao Guanghua, Li Qian, Wang Wei, Chen Yao, Zhao Ting, Li Fang, Zou Ye, Wu Huiyu, Yang Liuqing*, Wu Xiangyang*. Effects of chromium malate on glycometabolism, glycometabolism-related enzyme levels and lipid metabolism in type 2 diabetic rats: A dose–response and curative effects study. Journal of Diabetes Investigation. 2015.6(4): 396-407. (SCI, IF=3.147)

[20] Feng Weiwei, Wu Huiyu, Li Qian, Zhou Zhaoxiang, Chen Yao, Zhao Ting, Feng Yun, Mao Guanghua, Li Fang, Yang Liuqing*, Wu Xiangyang*. Evaluation of 90-day repeated dose oral toxicity，glycometabolism, learning and memory ability and related enzyme of chromium malate supplementation in sprague-dawley rats. Biological Trace Element Research. 2015.168(1): 181-195. (SCI, IF=1.798)

[21] Feng Weiwei, Zhang Weijie, Zhao Ting, Mao Guanghua, Wang Wei, Wu Xueshan, Zhou Zhaoxiang, Huang Jing, Bao Yongtuan, Yang Liuqing*, Wu Xiangyang*. Evaluation of the reproductive toxicity，glycometabolism, glycometabolism-related enzyme levels and lipid metabolism of chromium malate supplementation in sprague-dawley rats. Biological Trace Element Research. 2015. 168(1): 150-168. (SCI, IF=1.798)

[22] Feng Weiwei, Zhao Ting, Mao Guanghua, Zou Ye, Zheng Daheng, Wang Wei, Zheng Wei, Zhu Yang, Gu Xiaoyun, Yang Liuqing*, Wu Xiangyang*. A Novel Ointment to Treat Donor Sites in Scald Mouse. Latin American Journal of Pharmacy. 2015, 34(5).907-916. (SCI, IF=0.319)

[23] Feng Weiwei, Zhao Ting, Zhou Ye, Li Fang, Zou Ye, Bai Shiqi, Wang Wei, Yang Liuqing*, Wu Xiangyang*. Optimization of enzyme-assisted extraction and characterization of collagen from Chinese sturgeon (Acipenser sturio Linnaeus) skin. Pharmacognosy Magazine. 2013. 36(9), s32-s37. (SCI, IF=1.525)

授权专利

[1] 仰榴青, 冯伟伟, 张祯, 许海, 邹烨, 王未, 张敏, 邹艳敏, 吴向阳. 一种用于治疗皮肤烫伤的药物提取物软膏剂，中国发明专利, ZL 201210488242.0. 发文日：2014年1月6日.

[2] 仰榴青, 冯伟伟, 赵婷, 茆广华, 邹烨, 邹艳敏, 郑大恒, 任月娜, 吴向阳. 一种治疗皮肤烫伤的软膏剂, 中国发明专利, ZL 201210486467.2. 发文日：2013年11月26日.